| Week | Date | Opponent | Location |
|---|---|---|---|
| 1 | 8/15 | @ Buffalo Bills BUF | Highmark Stadium |
| 2 | 8/21 | @ Jacksonville Jaguars JAX | EverBank Stadium |
| 3 | 8/28 | Houston Texans HOU | Bank of America Stadium |
| 4 | 9/13 | Chicago Bears CHI | Bank of America Stadium |
| 5 | 9/20 | @ Atlanta Falcons ATL | Mercedes-Benz Stadium |
| 6 | 9/27 | @ Cleveland Browns CLE | Huntington Bank Field |
| 7 | 10/4 | Detroit Lions DET | Bank of America Stadium |
| 8 | Bye Week | N/A | |
| 9 | 10/18 | @ Philadelphia Eagles PHI | Lincoln Financial Field |
| 10 | 10/25 | Tampa Bay Buccaneers TB | Bank of America Stadium |
| 11 | 10/29 | @ Green Bay Packers GB | Lambeau Field |
| 12 | 11/8 | Denver Broncos DEN | Bank of America Stadium |
| 13 | 11/15 | @ New Orleans Saints NO | Caesars Superdome |
| 14 | 11/22 | Baltimore Ravens BAL | Bank of America Stadium |
| 15 | 11/30 | @ Tampa Bay Buccaneers TB | Raymond James Stadium |
| 16 | 12/6 | @ Minnesota Vikings MIN | US Bank Stadium |
| 17 | 12/13 | New Orleans Saints NO | Bank of America Stadium |
| 18 | 12/20 | Cincinnati Bengals CIN | Bank of America Stadium |
| 19 | TBA | @ Pittsburgh Steelers PIT | Acrisure Stadium |
| 20 | 1/3 | Seattle Seahawks SEA | Bank of America Stadium |
| 21 | TBA | Atlanta Falcons ATL | Bank of America Stadium |
| 22 | TBA | TBA | Bank of America Stadium |
| 23 | TBA | TBA | Bank of America Stadium |
| 24 | TBA | TBA | Bank of America Stadium |
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