| Week | Date | Opponent | Location |
|---|---|---|---|
| 1 | 8/8 | Cleveland Browns CLE | Bank of America Stadium |
| 2 | 8/16 | @ Houston Texans HOU | NRG Stadium |
| 3 | 8/21 | Pittsburgh Steelers PIT | Bank of America Stadium |
| 4 | 9/7 | @ Jacksonville Jaguars JAX | TIAA Bank Field |
| 5 | 9/14 | @ Arizona Cardinals ARZ | State Farm Stadium |
| 6 | 9/21 | Atlanta Falcons ATL | Bank of America Stadium |
| 7 | 9/28 | @ New England Patriots NE | Gillette Stadium |
| 8 | 10/5 | Miami Dolphins MIA | Bank of America Stadium |
| 9 | 10/12 | Dallas Cowboys DAL | Bank of America Stadium |
| 10 | 10/19 | @ New York Jets NYJ | MetLife Stadium |
| 11 | 10/26 | Buffalo Bills BUF | Bank of America Stadium |
| 12 | 11/2 | @ Green Bay Packers GB | Lambeau Field |
| 13 | 11/9 | New Orleans Saints NO | Bank of America Stadium |
| 14 | 11/16 | @ Atlanta Falcons ATL | Mercedes-Benz Stadium |
| 15 | 11/24 | @ San Francisco 49ers SF | Levi's Stadium |
| 16 | 11/30 | Los Angeles Rams LAR | Bank of America Stadium |
| 17 | TBA | Bye Week | N/A |
| 18 | 12/14 | @ New Orleans Saints NO | Caesars Superdome |
| 19 | 12/21 | Tampa Bay Buccaneers TB | Bank of America Stadium |
| 20 | TBA | Seattle Seahawks SEA | Bank of America Stadium |
| 21 | TBA | @ Tampa Bay Buccaneers TB | Raymond James Stadium |
| 22 | TBA | TBA | Bank of America Stadium |
| 23 | TBA | TBA | Bank of America Stadium |
| 24 | TBA | TBA | Bank of America Stadium |
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